11-Ketodihydrotestosterone

11-Ketodihydrotestosterone
Names
	IUPAC name 17β-Hydroxy-5α-androstane-3,11-dione
	Systematic IUPAC name (1S,3aS,3bS,5aS,9aS,9bS,11aS)-1-Hydroxy-9a,11a-dimethyltetradecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione
	Other names 11-Oxodihydrotestosterone; 5α-Androstan-17β-ol-3,11-dione; 11-KDHT
Identifiers
CAS Number	32694-37-4 ;
3D model (JSmol)	Interactive image;
ChemSpider	9372548;
PubChem CID	11197479;
UNII	DX994972WA ;
CompTox Dashboard (EPA)	DTXSID201043344 ;
	InChI InChI=1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h11,13-14,16-17,22H,3-10H2,1-2H3/t11-,13-,14-,16-,17+,18-,19-/m0/s1 Key: RSQKILYTRHKUIJ-HZGXJFKTSA-N;
	SMILES C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@H]4O)C;
Properties
Chemical formula	C19H28O3
Molar mass	304.43 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

11-Ketodihydrotestosterone (11-KDHT), also known as 5α-androstan-17β-ol-3,11-dione, is an endogenous, naturally occurring steroid and androgen prohormone that is produced primarily, if not exclusively, in the adrenal glands.^[1] It is closely related to 11β-hydroxyandrostenedione (11β-KA4), adrenosterone (11-ketoandrostenedione; 11-KA4), and 11-ketotestosterone (11-KT), which are also produced in the adrenal glands.^[1]

References

^ ^a ^b Pretorius E, Arlt W, Storbeck KH (February 2017). "A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids" (PDF). Molecular and Cellular Endocrinology. 441: 76–85. doi:10.1016/j.mce.2016.08.014. PMID 27519632. S2CID 4079662.

[PretoriusArlt2016-1] Pretorius E, Arlt W, Storbeck KH (February 2017). "A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids" (PDF). Molecular and Cellular Endocrinology. 441: 76–85. doi:10.1016/j.mce.2016.08.014. PMID 27519632. S2CID 4079662.

[1]

See also

References