Interleukin-22 receptor

interleukin 22 receptor, alpha 1
Identifiers
SymbolIL22RA1
Alt. symbolsIL22R
NCBI gene58985
HGNC13700
OMIM605457
RefSeqNM_021258
UniProtA8K839
Other data
LocusChr. 1 p36.11
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StructuresSwiss-model
DomainsInterPro
interleukin 22 receptor, alpha 2
Identifiers
SymbolIL22RA2
NCBI gene116379
HGNC14901
OMIM606648
RefSeqNM_181310
UniProtQ969J5
Other data
LocusChr. 6 q24.1-24.2
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StructuresSwiss-model
DomainsInterPro

Interleukin-22 receptor is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1[1] and IL-10Rβ2[1] subunits.

References

  1. ^ a b Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL (2000). "Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R". J. Biol. Chem. 275 (40): 31335–9. doi:10.1074/jbc.M005304200. PMID 10875937.


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