Hexethal |
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| Other names | Sodium 5-ethyl-5-hexylbarbiturate, Ortal, Hebaral |
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sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate
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| Formula | C12H19N2NaO3 |
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| Molar mass | 262.285 g·mol−1 |
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| 3D model (JSmol) | |
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[Na+].O=C1/N=C(/[O-])NC(=O)C1(CCCCCC)CC
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InChI=1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 YKey:HXUAXLUDTCGASZ-UHFFFAOYSA-M Y
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Hexethal (Ortal) is a barbiturate derivative invented in the 1940s. It has sedative, anxiolytic, muscle relaxant, and anticonvulsant properties, and was used primarily as an anaesthetic in veterinary medicine.[1]
Hexethal is considered similar in effects to pentobarbital, with a very fast onset of action but short duration of effects.
References
- ^ Butler TC (October 1950). "The rate of penetration of barbituric acid derivatives into the brain". The Journal of Pharmacology and Experimental Therapeutics. 100 (2): 219–26. PMID 14784958.
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| Barbiturates | |
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| Kava constituents |
- 10-Methoxyyangonin
- 11-Methoxyyangonin
- 11-Hydroxyyangonin
- Desmethoxyyangonin
- 11-Methoxy-12-hydroxydehydrokavain
- 7,8-Dihydroyangonin
- Kavain
- 5-Hydroxykavain
- 5,6-Dihydroyangonin
- 7,8-Dihydrokavain
- 5,6,7,8-Tetrahydroyangonin
- 5,6-Dehydromethysticin
- Methysticin
- 7,8-Dihydromethysticin
- Yangonin
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| Monoureides | |
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| Neuroactive steroids | |
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| Nonbenzodiazepines |
- Others: Adipiplon
- CGS-8216
- CGS-9896
- CGS-13767
- CGS-20625
- CL-218,872
- CP-615,003
- CTP-354
- ELB-139
- GBLD-345
- Imepitoin
- JM-1232
- L-838,417
- Lirequinil (Ro41-3696)
- NS-2664
- NS-2710
- NS-11394
- Pipequaline
- ROD-188
- RWJ-51204
- SB-205,384
- SX-3228
- TGSC01AA
- TP-003
- TPA-023
- TP-13
- U-89843A
- U-90042
- Viqualine
- Y-23684
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| Others/unsorted |
- 3-Hydroxybutanal
- α-EMTBL
- AA-29504
- Alogabat
- Avermectins (e.g., ivermectin)
- Bromide compounds (e.g., lithium bromide, potassium bromide, sodium bromide)
- Carbamazepine
- Chloralose
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- DEABL
- Deuterated etifoxine
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- DS2
- Efavirenz
- Etazepine
- Etifoxine
- Fenamates (e.g., flufenamic acid, mefenamic acid, niflumic acid, tolfenamic acid)
- Fluoxetine
- Flupirtine
- Hopantenic acid
- KRM-II-81
- Lanthanum
- Lavender oil
- Lignans (e.g., 4-O-methylhonokiol, honokiol, magnolol, obovatol)
- Loreclezole
- Menthyl isovalerate (validolum)
- Monastrol
- Nicotinic acid
- Nicotinamide
- Org 25,435
- Phenytoin
- Propanidid
- Retigabine (ezogabine)
- Safranal
- Seproxetine
- Stiripentol
- Sulfonylalkanes (e.g., sulfonmethane (sulfonal), tetronal, trional)
- Terpenoids (e.g., borneol)
- Topiramate
- Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol)
- Unsorted benzodiazepine site positive modulators: α-Pinene
- MRK-409 (MK-0343)
- TCS-1105
- TCS-1205
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See also: Receptor/signaling modulators • GABA receptor modulators • GABA metabolism/transport modulators |