Valproate pivoxil (Pivadin, Valproxen) is an anticonvulsant used in the treatment of epilepsy.[1] It is the pivaloyloxymethyl ester derivative of valproic acid.[2] It is likely a prodrug of valproic acid, as pivoxil esters are commonly employed to make prodrugs in medicinal chemistry.
See also
References
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| Transporter | | GATTooltip GABA transporter | |
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| VIAATTooltip Vesicular inhibitory amino acid transporter | |
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| Enzyme | | GADTooltip Glutamate decarboxylase |
- Activators: 3-Methyl-GABA
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| GABA-TTooltip γ-Aminobutyrate aminotransferase |
- Activators: 3-Methyl-GABA
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| Other | |
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- See also
- Receptor/signaling modulators
- GABA receptor modulators
- GABAA receptor positive modulators
- Glutamate metabolism/transport modulators
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See also: Receptor/signaling modulators |
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| Calcium | | VDCCsTooltip Voltage-dependent calcium channels | | Blockers |
- R-type-selective: SNX-482
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| Activators | |
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| Potassium | | VGKCsTooltip Voltage-gated potassium channels | | Blockers |
- KCNQ (Kv7)-specific: Linopirdine
- XE-991
- Spooky toxin (SsTx)
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| Activators | |
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| IRKsTooltip Inwardly rectifying potassium channel | | Blockers | |
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| Activators |
- GIRKTooltip G protein-coupled inwardly rectifying potassium channel-specific: ML-297 (VU0456810)
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| KCaTooltip Calcium-activated potassium channel | |
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| K2PsTooltip Tandem pore domain potassium channel | |
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| Sodium | | VGSCsTooltip Voltage-gated sodium channels | | Blockers |
- Analgesics: AZD-3161
- DSP-2230
- Funapide
- GDC-0276
- NKTR-171
- PF-04531083
- PF-05089771
- Ralfinamide
- Raxatrigine
- RG7893 (GDC-0287)
- Suzetrigine
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| Activators | |
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| ENaCTooltip Epithelial sodium channel | |
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| ASICsTooltip Acid-sensing ion channel | |
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| Chloride | | CaCCsTooltip Calcium-activated chloride channel | |
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| CFTRTooltip Cystic fibrosis transmembrane conductance regulator | |
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| Unsorted | |
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| Others | | TRPsTooltip Transient receptor potential channels | |
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| LGICsTooltip Ligand gated ion channels | |
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See also: Receptor/signaling modulators • Transient receptor potential channel modulators |