Rolicyclidine (PCPy) is a dissociative anesthetic that is similar in effects to phencyclidine, but is slightly less potent and has fewer stimulant effects.[2] It instead produces a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.[3] Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known.
See also
References
- ^ Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
- ^ Kalir A, Edery H, Pelah Z, Balderman D, Porath G (May 1969). "1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity". Journal of Medicinal Chemistry. 12 (3): 473–7. doi:10.1021/jm00303a030. PMID 4977945.
- ^ DEA Microgram Bulletin, 8, 143, 1975
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Psychedelics (5-HT2AR agonists) |
- Tryptamines (e.g., DMT, psilocin, psilocybin, bufotenin, 5-MeO-DMT, AMT)
- Phenethylamines (e.g., mescaline, 2C-B, DOM, MDA, TMA, 2C-B-FLY, 25I-NBOMe)
- Lysergamides (e.g., LSD, ergine, isoergine)
- Others (e.g., quipazine, efavirenz)
- For a full list of serotonergic psychedelics, see the navbox here and the list here instead.
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Dissociatives (NMDAR antagonists) | |
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Deliriants (mAChR antagonists) | |
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Cannabinoids (CB1R agonists) | | Natural | |
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| Synthetic | | AM-x |
- AM-087
- AM-251
- AM-279
- AM-281
- AM-356
- AM-374
- AM-381
- AM-404
- AM-411
- AM-630
- AM-661
- AM-678
- AM-679
- AM-694
- AM-735
- AM-855
- AM-881
- AM-883
- AM-905
- AM-906
- AM-919
- AM-926
- AM-938
- AM-1116
- AM-1172
- AM-1220
- AM-1221
- AM-1235
- AM-1241
- AM-1248
- AM-1710
- AM-1714
- AM-1902
- AM-2201
- AM-2212
- AM-2213
- AM-2232
- AM-2233
- AM-2389
- AM-3102
- AM-4030
- AM-4054
- AM-4056
- AM-4113
- AM-6545
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| CP x |
- CP 47,497
- CP 55,244
- CP 55,940
- (±)-CP 55,940
- (+)-CP 55,940
- (-)-CP 55,940
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| HU-x | |
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| JWH-x | |
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| Misc. | |
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- For a full list of cannabinoids, see the navbox here and the list here instead.
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| κOR agonists | |
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| GABAAR agonists | |
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Inhalants (mixed MoATooltip mechanism of action) | |
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| Others |
- Aminochromes (e.g., adrenochrome, adrenolutin)
- Carbogen
- Certain GABAA receptor positive allosteric modulators (nonbenzodiazepines/Z-drugs) (e.g., eszopiclone, zaleplon, zolpidem, zopiclone)
- CI-966
- Cryogenine
- Glaucine
- Hallucinogenic bolete mushrooms (e.g., Lanmaoa asiatica)
- Harmala alkaloids/β-carbolines (e.g., harmaline, 6-methoxyharmalan)
- Iboga alkaloids/azepinoindoles (e.g., ibogaine)
- Isoaminile
- Noscapine
- Nutmeg (e.g., myristicin, elemicin)
- Oneirogens (e.g., Calea zacatechichi, galantamine, nicotine, Silene capensis)
- Prenoxdiazine
- Pukateine
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- See also: Psychedelics
- Entactogens
- Stimulants
- Depressants
- List of hallucinogens
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| D1-like | | Agonists | |
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| PAMs |
- Tetrahydroisoquinolines: DETQ
- DPTQ
- Mevidalen
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| Antagonists |
- Others: Berupipam
- Ecopipam
- EEDQ
- Metitepine (methiothepin)
- Odapipam
- Perlapine
- SCH-23390
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| D2-like | | Agonists |
- Dihydrexidine derivatives: 2-OH-NPA
- Ciladopa
- Dihydrexidine
- Dinoxyline
- N,N-Propyldihydrexidine
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| Antagonists | |
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- See also: Receptor/signaling modulators
- Adrenergics
- Serotonergics
- Monoamine reuptake inhibitors
- Monoamine releasing agents
- Monoamine metabolism modulators
- Monoamine neurotoxins
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| AMPARTooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor | |
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| KARTooltip Kainate receptor | |
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| NMDARTooltip N-Methyl-D-aspartate receptor |
- Unsorted: Allosteric modulators: AGN-241751
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- See also: Receptor/signaling modulators
- Metabotropic glutamate receptor modulators
- Glutamate metabolism/transport modulators
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