Dieticyclidine (PCDE), or diethylphenylcyclohexylamine, is a psychoactive drug and research chemical of the arylcyclohexylamine chemical class related to phencyclidine (PCP) and eticyclidine (PCE). It acts as an NMDA receptor antagonist but has low potency and acts mainly as a prodrug for eticyclidine.[1][2]
References
- ^ Cho AK, Hiramatsu M, Schmitz DA, Landaw EM, Chang AS, Ramamurthy S, Jenden DJ (1993). "A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine". Drug Metabolism and Disposition. 21 (1): 125–32. PMID 8095205.
- ^ Cho AK, Hiramatsu M, Schmitz DA, Vargas HM, Landaw EM (March 1993). "A behavioral and pharmacokinetic study of the actions of phenylcyclohexyldiethylamine and its active metabolite, phenylcyclohexylethylamine". The Journal of Pharmacology and Experimental Therapeutics. 264 (3): 1401–5. PMID 8450474.
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Psychedelics (5-HT2AR agonists) |
- Tryptamines (e.g., DMT, psilocin, psilocybin, bufotenin, 5-MeO-DMT, AMT)
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Dissociatives (NMDAR antagonists) | |
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Deliriants (mAChR antagonists) | |
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Cannabinoids (CB1R agonists) | | Natural | |
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| Synthetic | | AM-x |
- AM-087
- AM-251
- AM-279
- AM-281
- AM-356
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- AM-4113
- AM-6545
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| CP x |
- CP 47,497
- CP 55,244
- CP 55,940
- (±)-CP 55,940
- (+)-CP 55,940
- (-)-CP 55,940
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| HU-x | |
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| JWH-x | |
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Inhalants (mixed MoATooltip mechanism of action) | |
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- See also: Psychedelics
- Entactogens
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- List of hallucinogens
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| D1-like | | Agonists | |
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| PAMs |
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| Antagonists |
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| D2-like | | Agonists |
- Dihydrexidine derivatives: 2-OH-NPA
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- N,N-Propyldihydrexidine
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| Antagonists | |
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- See also: Receptor/signaling modulators
- Adrenergics
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| KARTooltip Kainate receptor | |
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| NMDARTooltip N-Methyl-D-aspartate receptor |
- Unsorted: Allosteric modulators: AGN-241751
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- See also: Receptor/signaling modulators
- Metabotropic glutamate receptor modulators
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